Intravesical instillation of oxybutynin hydrochloride therapy for patients with a neuropathic bladder

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Intravesical Oxybutynin for Neurogenic Bladder in Children

Neuropathic bladder dysfunction caused by spinal cord disease may lead to irreversible renal damage and urinary incontinence. The majority of affected children can be successfully managed with standard medical treatment such as oral anti-cholinergic medication (typically oxybutynin or tolterodine) with or without Clean Intermittent Catheterization (CIC). The efficacy of this treatment, however,...

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Modified Intravesical Oxybutynin Chloride Therapy in Children with Neurogenic Bladder: a Ten-year Follow-up

Hypothesis / aims of study Children with spinal cord disorders can present with neurogenic bladder, a condition in which the bladder partly or completely loses its ability to store urine and void at low pressure. A bladder with low compliance may cause urinary incontinence, which negatively impacts quality of life and renal function. Long-term high pressure neurogenic bladder can increase the r...

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Does oxybutynin hydrochloride cause arrhythmia in children with bladder dysfunction?

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Intravesical oxybutynin for children with poorly compliant neurogenic bladder: a systematic review.

PURPOSE Children with neurogenic bladder and poor bladder compliance are usually treated with bladder catheterization and oral anticholinergic medication. They may become nonresponders to the drug or present with severe side effects. We evaluated the effectiveness and tolerability of intravesical oxybutynin in children with poorly compliant neurogenic bladder. MATERIALS AND METHODS We conduct...

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ژورنال

عنوان ژورنال: Spinal Cord

سال: 1994

ISSN: 1362-4393,1476-5624

DOI: 10.1038/sc.1994.5